Endemic Goiter due to Thyroglobulin Gene Abnormality and Social Ostracism

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Endemic goiter due to thyroglobulin gene abnormality and social ostracism.

Endemic goiter is clustered occurrences of goiter affecting more than 10% of the population in particular regions. The majority cases are attributed to environmental factors such as iodine deficiency, or food and water containing goiter-causing agents called goitrogens. We report a new type of endemic goiter where the basic abnormality was not due to environment factors, but to thyroglobulin ge...

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ENDEMIC GOITER. The Adaptation of Man to Iodine Deficiency. By John B. Stanbury, Gordon L. Brownell, Douglas S. Riggs, Hector Perinetti, Juan Itoiz, and Enrique B. Del Castillo. Cambridge, Massachusetts, Harvard University Press, 1954. 209 pp. $4.00. This monograph reports the results obtained by the Andean Goiter Expedition, a joint project undertaken by Harvard Medical School, the University ...

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“Goiter” means thyroid enlargement, and “endemic” means frequent in a certain locality. The problem is from what volume and up a thyroid is considered to be large enough as to be classified as goiter and also from what prevalence and up an area is considered to be endemic. It is obvious that by playing with these definitions one may increase or decrease the prevalence of goiter perceived in an ...

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ژورنال

عنوان ژورنال: Endocrine Journal

سال: 2007

ISSN: 0918-8959,1348-4540

DOI: 10.1507/endocrj.k07-020